Genetic mapping of the ecotropic virus-inducing locus Akv-2 of the AKR mouse
نویسندگان
چکیده
A combination of somatic cell hybridization and standard mendelian breeding techniques was used to map the AKR ecotropic virus inducibility locus Akv-2 to the centromeric end of chromosome 16. This assignment of Akv-2 further emphasizes the endogenous ecotropic retroviruses are inserted at multiple sites in mouse chromosomes.
منابع مشابه
Brief DeNnitive Report
Chromosomal genes for the induction of infectious murine leukemia viruses (MuLV) have now been identified and mapped in several inbred mouse strains. In the AKR mouse, the prototype for high virus, high leukemic mice, two independently segregating loci for ecotropic virus inducibility have been defined (1). One of these, designated Akv-l, was mapped to mouse chromosome 7 (2) and has been shown ...
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عنوان ژورنال:
- The Journal of Experimental Medicine
دوره 152 شماره
صفحات -
تاریخ انتشار 1980